Regulatory data is for reference only. Always verify with the official regulator before making formulation decisions. Last refreshed: 10/13/2026.
Ingredients/4,4'-Methylenedianiline
4,4'-MethylenedianilineCAS 101-77-9
EU CosIng II — prohibitedECHA SVHC — candidateASEAN II — prohibitedChina NMPA — prohibitedUK OPSS — prohibitedBrazil ANVISA — prohibited
Is 4,4'-Methylenedianiline restricted in cosmetics?
4,4'-Methylenedianiline is prohibited in EU CosIng, ASEAN, China NMPA, UK OPSS and Brazil ANVISA. Markets not named here hold no entry for it, which is not a clearance.
- CAS
- 101-77-9
- INCI
- 4,4'-Methylenedianiline
- Data refreshed
- 2026-10-13
Regulatory status
| Source | Status | Annex / Details | Limit / Conditions | Last updated |
|---|---|---|---|---|
| EU CosIng | prohibited | Annex II | — | — |
| ECHA SVHC | candidate | 2011-12-19 | Carcinogen (Cat 1B), Reprotoxic (Cat 2) | 12/19/2011 |
| ASEAN | prohibited | Annex II | — | — |
| China NMPA | prohibited | — | — | 10/7/2026 |
| UK OPSS | prohibited | — | Source: legislation.gov.uk retained EU Regulation 1223/2009 Annex Ii | 10/5/2026 |
| Brazil ANVISA | prohibited | — | — | 10/7/2026 |
What this means
4,4'-Methylenedianiline has regulatory signals in EU CosIng, ECHA SVHC, ASEAN, China NMPA, UK OPSS, Brazil ANVISA. Review the source links above for the official conditions and latest updates.
Recent regulatory changes
No recorded regulatory changes for 4,4'-Methylenedianiline yet.
Common questions
- Is 4,4'-Methylenedianiline restricted in EU cosmetics?
- 4,4'-Methylenedianiline is prohibited in EU cosmetics according to EU CosIng Annex II.
- Is 4,4'-Methylenedianiline on the ECHA SVHC candidate list?
- 4,4'-Methylenedianiline is listed on the ECHA SVHC candidate list since 2011-12-19.
- Is 4,4'-Methylenedianiline restricted under the ASEAN Cosmetic Directive?
- 4,4'-Methylenedianiline is prohibited under the ASEAN Cosmetic Directive Annex II.
- Is 4,4'-Methylenedianiline restricted in China NMPA?
- 4,4'-Methylenedianiline is prohibited in cosmetics under China NMPA.
- Is 4,4'-Methylenedianiline restricted in UK OPSS?
- 4,4'-Methylenedianiline is prohibited in cosmetics under UK OPSS.
- Is 4,4'-Methylenedianiline restricted in Brazil ANVISA?
- 4,4'-Methylenedianiline is prohibited in cosmetics under Brazil ANVISA.
- What is the CAS number for 4,4'-Methylenedianiline?
- The CAS number for 4,4'-Methylenedianiline is 101-77-9.
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