Is 5-Chloro-2-(2,4-dichlorophenoxy)phenol restricted in EU cosmetics?

5-Chloro-2-(2,4-dichlorophenoxy)phenol is listed in EU CosIng Annex V.

Is 5-Chloro-2-(2,4-dichlorophenoxy)phenol restricted by the FDA in the US?

5-Chloro-2-(2,4-dichlorophenoxy)phenol is on the FDA's restricted substances list for cosmetics (CFR 21 CFR 310.545): Prohibited from OTC antiseptic wash products (2016 rule). Still allowed in toothpaste (Colgate Total) under prescription drug approval.

Is 5-Chloro-2-(2,4-dichlorophenoxy)phenol restricted under the ASEAN Cosmetic Directive?

5-Chloro-2-(2,4-dichlorophenoxy)phenol is restricted under the ASEAN Cosmetic Directive Annex III with a maximum concentration of (a) 0.3 % (b) 0.2 %.

What is the CAS number for 5-Chloro-2-(2,4-dichlorophenoxy)phenol?

The CAS number for 5-Chloro-2-(2,4-dichlorophenoxy)phenol is 3380-34-5.

Regulatory data is for reference only. Always verify with the official regulator before making formulation decisions. Last refreshed: 8/29/2026.

Ingredients/5-Chloro-2-(2,4-dichlorophenoxy)phenol

5-Chloro-2-(2,4-dichlorophenoxy)phenolCAS 3380-34-5

EU CosIng V — preservativeFDA CFR 21 CFR 310.545 — restrictedASEAN III — restricted

Regulatory status

Source	Status	Annex / Details	Limit / Conditions	Last updated
EU CosIng	preservative	Annex V	0.3%	—
FDA	restricted	Annex CFR 21 CFR 310.545	Prohibited from OTC antiseptic wash products (2016 rule). Still allowed in toothpaste (Colgate Total) under prescription drug approval.	—
ASEAN	restricted	Annex III	(a) 0.3 % (b) 0.2 %	—

What this means

5-Chloro-2-(2,4-dichlorophenoxy)phenol has regulatory signals in EU CosIng, FDA, ASEAN. Review the source links above for the official conditions and latest updates.

Common questions

Is 5-Chloro-2-(2,4-dichlorophenoxy)phenol restricted in EU cosmetics?: 5-Chloro-2-(2,4-dichlorophenoxy)phenol is listed in EU CosIng Annex V.
Is 5-Chloro-2-(2,4-dichlorophenoxy)phenol restricted by the FDA in the US?: 5-Chloro-2-(2,4-dichlorophenoxy)phenol is on the FDA's restricted substances list for cosmetics (CFR 21 CFR 310.545): Prohibited from OTC antiseptic wash products (2016 rule). Still allowed in toothpaste (Colgate Total) under prescription drug approval.
Is 5-Chloro-2-(2,4-dichlorophenoxy)phenol restricted under the ASEAN Cosmetic Directive?: 5-Chloro-2-(2,4-dichlorophenoxy)phenol is restricted under the ASEAN Cosmetic Directive Annex III with a maximum concentration of (a) 0.3 % (b) 0.2 %.
What is the CAS number for 5-Chloro-2-(2,4-dichlorophenoxy)phenol?: The CAS number for 5-Chloro-2-(2,4-dichlorophenoxy)phenol is 3380-34-5.

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