Regulatory data is for reference only. Always verify with the official regulator before making formulation decisions. Last refreshed: 10/12/2026.
Ingredients/Brucine
BrucineCAS 357-57-3
EU CosIng II — prohibitedASEAN II — prohibitedHealth Canada — restrictedChina NMPA — prohibitedUK OPSS — prohibitedBrazil ANVISA — prohibited
Is Brucine restricted in cosmetics?
Brucine is prohibited in EU CosIng, ASEAN, China NMPA, UK OPSS and Brazil ANVISA and restricted in Health Canada. Markets not named here hold no entry for it, which is not a clearance.
- CAS
- 357-57-3
- INCI
- Brucine
- Data refreshed
- 2026-10-12
Regulatory status
| Source | Status | Annex / Details | Limit / Conditions | Last updated |
|---|---|---|---|---|
| EU CosIng | prohibited | Annex II | — | — |
| ASEAN | prohibited | Annex II | — | — |
| Health Canada | restricted | — | 0.1% | 10/7/2026 |
| China NMPA | prohibited | — | — | 10/7/2026 |
| UK OPSS | prohibited | — | Source: legislation.gov.uk retained EU Regulation 1223/2009 Annex Ii | 10/5/2026 |
| Brazil ANVISA | prohibited | — | — | 10/7/2026 |
What this means
Brucine has regulatory signals in EU CosIng, ASEAN, Health Canada, China NMPA, UK OPSS, Brazil ANVISA. Review the source links above for the official conditions and latest updates.
Recent regulatory changes
No recorded regulatory changes for Brucine yet.
Common questions
- Is Brucine restricted in EU cosmetics?
- Brucine is prohibited in EU cosmetics according to EU CosIng Annex II.
- Is Brucine restricted under the ASEAN Cosmetic Directive?
- Brucine is prohibited under the ASEAN Cosmetic Directive Annex II.
- Is Brucine restricted in Health Canada?
- Brucine is restricted in cosmetics under Health Canada.
- Is Brucine restricted in China NMPA?
- Brucine is prohibited in cosmetics under China NMPA.
- Is Brucine restricted in UK OPSS?
- Brucine is prohibited in cosmetics under UK OPSS.
- Is Brucine restricted in Brazil ANVISA?
- Brucine is prohibited in cosmetics under Brazil ANVISA.
- What is the CAS number for Brucine?
- The CAS number for Brucine is 357-57-3.
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