Regulatory data is for reference only. Always verify with the official regulator before making formulation decisions. Last refreshed: 10/12/2026.
Ingredients/4,4'-Bi-o-toluidine dihydrochloride
4,4'-Bi-o-toluidine dihydrochlorideCAS 612-82-8
EU CosIng II — prohibitedASEAN II — prohibitedChina NMPA — prohibitedUK OPSS — prohibitedBrazil ANVISA — prohibited
Is 4,4'-Bi-o-toluidine dihydrochloride restricted in cosmetics?
4,4'-Bi-o-toluidine dihydrochloride is prohibited in EU CosIng, ASEAN, China NMPA, UK OPSS and Brazil ANVISA. Markets not named here hold no entry for it, which is not a clearance.
- CAS
- 612-82-8
- INCI
- 4,4'-Bi-o-toluidine dihydrochloride
- Data refreshed
- 2026-10-12
Regulatory status
| Source | Status | Annex / Details | Limit / Conditions | Last updated |
|---|---|---|---|---|
| EU CosIng | prohibited | Annex II | — | — |
| ASEAN | prohibited | Annex II | — | — |
| China NMPA | prohibited | — | — | 10/7/2026 |
| UK OPSS | prohibited | — | Source: legislation.gov.uk retained EU Regulation 1223/2009 Annex Ii | 10/5/2026 |
| Brazil ANVISA | prohibited | — | — | 10/7/2026 |
What this means
4,4'-Bi-o-toluidine dihydrochloride has regulatory signals in EU CosIng, ASEAN, China NMPA, UK OPSS, Brazil ANVISA. Review the source links above for the official conditions and latest updates.
Recent regulatory changes
No recorded regulatory changes for 4,4'-Bi-o-toluidine dihydrochloride yet.
Common questions
- Is 4,4'-Bi-o-toluidine dihydrochloride restricted in EU cosmetics?
- 4,4'-Bi-o-toluidine dihydrochloride is prohibited in EU cosmetics according to EU CosIng Annex II.
- Is 4,4'-Bi-o-toluidine dihydrochloride restricted under the ASEAN Cosmetic Directive?
- 4,4'-Bi-o-toluidine dihydrochloride is prohibited under the ASEAN Cosmetic Directive Annex II.
- Is 4,4'-Bi-o-toluidine dihydrochloride restricted in China NMPA?
- 4,4'-Bi-o-toluidine dihydrochloride is prohibited in cosmetics under China NMPA.
- Is 4,4'-Bi-o-toluidine dihydrochloride restricted in UK OPSS?
- 4,4'-Bi-o-toluidine dihydrochloride is prohibited in cosmetics under UK OPSS.
- Is 4,4'-Bi-o-toluidine dihydrochloride restricted in Brazil ANVISA?
- 4,4'-Bi-o-toluidine dihydrochloride is prohibited in cosmetics under Brazil ANVISA.
- What is the CAS number for 4,4'-Bi-o-toluidine dihydrochloride?
- The CAS number for 4,4'-Bi-o-toluidine dihydrochloride is 612-82-8.
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