Source detection
CHANGE DETECTED
EU Annex VI source revision
The monitor captures the source text, effective date, market scope, and supporting evidence as soon as the revision is published.
EU Cosmetics RegulationScanning source
Cosmetics Regulatory Compliance & Intelligence Software
Checks your whole formula. Not just the ingredient.
For cosmetic brands, contract manufacturers and formulators. We check every ingredient at its actual concentration, for your actual product type, against all 11 markets at once. We then monitor them daily and tell you which formulas are affected when a rule changes.
30 minutes · live with your own formulations
Try a free search, no signup11 markets32,000+ ingredientsevery verdict cited
Radiance Day Cream (leave-on)
3 of 8 ingredients shown · 11 markets2.4s
Benzophenone-36.5%EU Annex VI · max 6% face Over limit
Ingredient B4.0%Within limits checked No flag
Ingredient C0.9%Within limits checked No flag
Concentration flag. Benzophenone-3 at 6.5% exceeds the EU Annex VI limit of 6% for face products. This formula is a leave-on face cream.
Illustrative example
Built on primary sources
EU CosIng Annexes II–VIUS FDA · MoCRAHealth Canada HotlistSCCS opinionsCIR assessmentsIARC monographsECHA SVHC listIFRA Standards
Check · from supplier PDF to decision-ready evidence
Turn a messy SDS into a market-ready compliance brief
One guided workflow handles the hard parts in sequence: capture the source, structure the formula, assess every market, and explain exactly what needs review.
From supplier SDS to a reviewable compliance briefCapture source data · confirm the formula · assess markets · explain the resultMolecular evidence graphCapture in progress
1Capture
2Structure
3Assess
4Explain
1. Source documentSDS · PDF
Start with the supplier record. The source remains attached to the extracted values.
Supplier-SDS_rev-04.pdf
Reading composition0%
2. Extract & reviewREVIEW GATE
Section 3 becomes a structured formula. Unclear names or values stay visible for review.
IngredientCAS%
Extracting...
Extracting...
Extracting...
Waiting for source document
3. Market assessment11 GROUPINGS
Compare the reviewed formula with available market-specific rules and conditions of use.
EUASEANUSCACNJPKRUKAUBRGCC
Waiting for reviewed rows
4. Compliance brief
Turn the assessment into a concise record of findings, evidence, and next actions.
Compliance briefVerdict preview · evidence attached
EU · Face productREVIEW
Benzophenone-36.5% / limit 6%
0.5 percentage points above the applicable limit.
SOURCE EU Cosmetics Regulation · Annex VI
NEXT Reformulate to ≤ 6%, then re-check
Waiting for completed assessment
From the same data, export audit-ready SDS and MoCRA documentation without rebuilding it by hand.
32,000+
Ingredients indexed
11
Markets checked
30+
Jurisdictions monitored
20+
Regulatory frameworks
11 markets your formula is checked against · 30+ underlying jurisdictions and 20+ frameworks feeding those verdicts
Check · every market, named
Eleven markets. Here is every one of them.
These are the regulators your formula is checked against on every tier.
EU CosINGASEANUS FDAHealth CanadaChina NMPAJapan MHLWKorea MFDSUK OPSSAustralia AICISBrazil ANVISAGCC GSO
Behind them, the database tracks 30+ jurisdictions and 20+ frameworks that feed each verdict.
Browse all ingredientsCheck · depth, not breadth
A longer market list doesn't help if the check is shallow
"Restricted in the EU" is not an answer. The question is whether your ingredient, at your percentage, in your product type, passes.
Benzophenone-3 in a leave-on face cream
EU · Annex VI · max 6%
5.5%limit 6%
Within the limit
6.5%limit 6%
Over the limit
Same ingredient, same product, one point apart, and two different answers. A tool that only knows "restricted in the EU" can't tell you which side of the line you're on.
Concentration-aware
Every ingredient is checked at the percentage you actually used, against each market's maximum.
Application-type aware
Application-specific limits are evaluated against the product type, rather than applying one restriction across every format.
Whole formula, every market
All ingredients together, across all 11 markets, with a verdict per market.
Cited, not asserted
Every verdict carries its annex or regulation reference, so your team can verify it.
Report · what is actually covered
One assessment, several compliance lenses, one traceable report
The report separates legal restrictions, scientific and industry screens, and optional retailer standards so your team can see what each finding means.
Market restrictions
Prohibited, restricted, not restricted and Unknown results remain distinct for each selected market grouping.
Use conditions
Concentration and product-type conditions are evaluated when the underlying source supports them.
Special screens
Fragrance allergens, IFRA, REACH SVHC, California Proposition 65, US MoCRA and PFAS signals.
Retailer standards
Selected retailer programmes can be added as a separate commercial-policy layer, not presented as law.
Formulation compliance reportAssessment snapshot · configurable across 11 market groupings
Executive summary
Market-readiness overview
Regulatory matrix
Concentration and conditions
Flagged ingredients and open actions
Ingredient inventory
Evidence and audit manifest
This is a regulatory screening and evidence report. It is not regulator approval, certification, or a substitute for a CPSR signed by a qualified safety assessor. MoCRA signal screening does not file facility registrations, product listings or serious adverse event reports with FDA.
Monitor
When a rule changes, know exactly which formulas need action.
We follow the change from the regulatory source to the compound, then through every formula and market in your portfolio. Your team receives a concise, ranked plan rather than a vague alert.
Regulatory change impact map
A detected source change is matched to compound records, then branches to the exact formulas, markets, and actions that need attention.
PORTFOLIO MONITORING ACTIVE
Matched compound records
3 RECORDS MATCHEDMATCHED
The detector reconciles identity, CAS number, and formula use. Only confirmed matches continue to the affected portfolio.
Benzophenone-3CAS 131-57-7REVIEW
PhenoxyethanolCAS 122-99-61 linked formula
Fragrance allergen setPortfolio watch8 linked formulas
Formula impact
2 ALERTS OPENRadiance Day Cream
EUReview now
Daily Shield SPF
EU · UKCheck concentration
Brightening Serum
EUNo action needed
Action queue created
Two formula reviews are ready with source evidence, affected markets, and a re-check action attached.
OWNER-READY TASKS
The monitoring trail retains the regulatory source, compound match, affected formula, market context, and recommended next action.
Monitored daily
Source changes are captured with the revision context your team needs to review them.
Compound to formula traceability
Move from the changed rule to the exact compound, formulas, variants, and markets it touches.
A prioritized plan, not noise
Each update arrives with the formula impact, evidence, owner-ready next step, and a re-check path.
Fix
Ask what to do about it, not just what's wrong
Finding the problem is the easy half. These are the tools that help you fix it.
Ask MollyRegulatory reasoning layer · formula aware11 markets · cited answersLiveRadiance Day Cream
Molly's answer is grounded in● evidence linked
Your formulaProduct typeEU Annex VISelected markets
Illustrative exchange · source-linked reasoningFORMULA · CONTEXT · EVIDENCE
Ask Molly
A copilot that answers against your own formulas and markets, with citations.
AI reformulation
Candidate replacements that keep the function and clear the markets you sell into.
PFAS screening
Structural screen plus total organic fluorine across your portfolio, with citations.
Embed · API
Run the same compliance check from your own system
Everything the platform does to a formula, a REST call can do too, so compliance can live inside your PLM, your LIMS, or your own product, instead of in another browser tab.
POST /api/v1/formula-check
curl -X POST https://www.themoleculelab.com/api/v1/formula-check \
-H "Authorization: Bearer tml_live_..." \
-H "Content-Type: application/json" \
-d '{
"product_type": "leave-on",
"ingredients": [
{ "name": "Benzophenone-3", "concentration": 6.5 }
]
}'Returns
market_summary · ingredients · assurance · requires_manual_review · request_id
9 REST endpoints
Formula checks across v1/v2/v3, evidence retrieval, formula storage, compliance lookups, ingredient search and shared formulas.
Bearer key auth
Scoped keys per organisation or partner, each limited to the markets it should see.
Same 11 markets
The identical engine as the app, with the same data, verdicts, and citations.
Audited every call
Audit records, rate-limit headers and a request_id on every response.
Building this into a product you sell? There's a partner tier with its own key management, per-client rate cards and monthly usage reporting for platforms embedding compliance for their own customers.
Live API access is available from the Standard tier upward.
Embed · security & deployment
Your formulas stay private and isolated
Proprietary composition data stays private and encrypted at rest, with a key generated for your organisation alone. It is never shared or used for training.
- AES-256-GCM encryption · per-org managed keys · TLS 1.3 in transit.
- Built to support GDPR Article 17 erasure and Article 20 portability · full audit log · isolated per organisation.
- On-premise and private-cloud tenancy are available on Enterprise for teams whose data cannot sit in shared infrastructure.
stored concentration record
Ingredient A9f3c·a17e·4b02·ffd1
Ingredient Bc8b5·20de·91a7·3e6c
Ingredient C47ae·e903·bb18·5d2f
Concentrations are encrypted with a key generated for your organisation alone.
AES-256-GCM
Encryption at rest
TLS 1.3
Encryption in transit
GDPR Art. 17/20
Erasure & portability support
On-prem ready
Private cloud tenancy
What regulatory professionals say
What compliance teams say
Feedback from regulatory professionals across the EU, North America and Asia.
“We used to spend entire days checking EU CosING and ASEAN annexes for every new formula. The Molecule Lab cut that to under a minute per substance. It genuinely changed how our team operates.”
SK
Sarah K.
Regulatory Affairs Manager
Personal Care Group, EU
“
“Having GHS classification, SVHC status, and ECHA Candidate List all in one search panel is exactly what we needed. Before this, we had three different ECHA tools open simultaneously.”
MR
Marco R.
Senior Formulation Scientist
Cosmetic Lab, Italy
“
“Canada Hotlist and FDA Prop 65 data in a single search? That's exactly what North American launches require. No other platform gives us both markets with this level of detail.”
JL
Jennifer L.
VP, Compliance & Safety
Skincare Brand, Canada
“
Bring the formula you're least sure about.
A 30-minute walkthrough with your own formulations and no commitment.